By Gabriele E. Lang
Diabetic retinopathy (DR), harm of the blood vessels within the retina, is among the difficulties that sufferers could face as a hassle of diabetes and is, in addition to different diabetic eye illnesses, the best unmarried reason behind blindness in built international locations. This booklet begins with the outline of the mechanisms of improvement and development of diabetic macular edema and with the characterization of the early levels of DR. An cutting edge strategy of multimedial mapping tools which permits to distinguish among 3 DR phenotypes is extra defined. the factors and novel ways of laser remedy in addition to present surgical recommendations and remedy suggestions are mentioned. extra contributions examine the pathology of diffuse macular edema and the results for surgical procedure, the remedy of DR with triamcinolone and its problems, and the appliance of somatostatin analogues. a brand new healing strategy is using vascular endothelial progress issue inhibitors in diabetic macular edema. the quantity concludes with articles at the most modern techniques of posterior vitreous detachment by way of pharmacologic vitreolysis and the explicit protein kinase C subtype Гџ inhibitor ruboxistaurin mesylate. To ophthalmologists and diabetes future health care execs drawn to diabetic eye sickness this ebook is an important up-date.
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Ophthalmic Surg Lasers 2000;31:182–186. Brown JC, Solomon SD, Bressler SB, Schachat AP, Di Bernardo C, Bressler N: Detection of diabetic foveal edema. Arch Ophthalmol 2004;122:330–335. Panozzo G, Gusson E, Parolini B, Mercanti A: Role of OCT in the diagnosis and follow up of diabetic macular edema. Semin Ophthalmol 2003;18:74–81. Strom C, Sander B, Laresen N, Larsen M, Lund-Andersen H: Diabetic macular edema assessed with optical coherence tomography and stereo fundus photography. Invest Ophthalmol Vis Sci 2002;43:241–245.
In this study, HbA1C levels were stabilized during the entire 2-year study period. Microaneurysm counts on fundus photographs and retinal thickness measurements were determined for each patient at 6-month intervals. The number of microaneurysms increased steadily throughout the 2-year study period in spite of the patients’ stabilized metabolic control, with more microaneurysms counted in the eyes of patients with worse glucose control. Microaneurysm formation rates during the 2-year study period varied widely among different patients.
Ophthalmologica 2005;219:86–92. Hee MR, Puliafito CA, Duker JS, Reichel E, Coker JG, Wilkins JR, Schuma JS, Swanson EA, Fujimoto JG: Topography of diabetic macular edema with optical coherence tomography. Opthalmology 1998;105:360–370. Larsen M, Wang M, Sander B: Overnight thickness variation in diabetic macular edema. Invest Ophthalmol Vis Sci 2005;47:2313–2316. Schaudig UH, Glaefke C, Scholz F, Richard G: Optical coherence tomography for retinal thickness measurement in diabetic patients without clinically significant macular edema.
Diabetic Retinopathy by Gabriele E. Lang