Download e-book for kindle: Device Therapy in Heart Failure by Mauricio Velez MD, Nancy K. Sweitzer MD, PhD (auth.),

By Mauricio Velez MD, Nancy K. Sweitzer MD, PhD (auth.), William H. Maisel (eds.)

ISBN-10: 1588299945

ISBN-13: 9781588299949

Heart failure impacts over five million sufferers within the usa on my own, and is a protracted and debilitating affliction. whereas a few pharmacologic treatments have proven various levels of effectiveness, many fresh advances within the therapy of center failure has concerned with equipment dependent remedies. In machine treatment in middle Failure, William H. Maisel and a panel of professionals at the use and implementation of gadget established treatments supply a finished review of the present and constructing applied sciences which are used to regard middle failure. person chapters offer an in-depth research of units similar to CRT’s and ICD’s, whereas broader themes corresponding to the pathophysiology of middle failure and its present clinical treatments also are mentioned. extra issues contain Pacing and Defibrillation for Atrial Arrhythmias, Atrial traumatic inflammation Ablation, and Percutaneous therapy of Coronary Artery Disease.

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As a consequence, carbonic anhydrase inhibitors are used infrequently in the management of heart failure patients. By contrast, loop-type diuretics, of which furosemide is a prototypical agent, are the cornerstone of heart failure therapy. These agents inhibit the Na+ 2Cl– K+ co-transporter at the thick ascending limb of the loop of Henle and are extremely effective natriuretic agents, capable of increasing the fractional excretion of sodium (FENA) to 25% of the filtered sodium load. , hydrochlorothiazide, metolazone) inhibit the Na+ Cl– cotransporter in the distal convoluted tubule, and when used alone, they are associated with only a modest natriuretic effect (5–8% of filtered sodium load, 1/5–1/3 potency compared to loop diuretics).

Kim S, Ohta K, Hamaguchi A, Yukimura T, Miura K, Iwao H. Angiotensin II induces cardiac phenotypic modulation and remodeling in vivo in rats. Hypertension 1995;25:1252–1259. 52. Kim S, Iwao H. Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal disease. Pharmacological Reviews 2000;52:11–34. 53. Latini R, Masson S, Anand I, et al. The comparative prognostic value of plasma neurohormones at baseline in patients with heart failure enrolled in Val-HeFT. European Heart Journal 2004;25:292–299.

Lancet 2008;372(9641):817–821. 51. Kim S, Ohta K, Hamaguchi A, Yukimura T, Miura K, Iwao H. Angiotensin II induces cardiac phenotypic modulation and remodeling in vivo in rats. Hypertension 1995;25:1252–1259. 52. Kim S, Iwao H. Molecular and cellular mechanisms of angiotensin II-mediated cardiovascular and renal disease. Pharmacological Reviews 2000;52:11–34. 53. Latini R, Masson S, Anand I, et al. The comparative prognostic value of plasma neurohormones at baseline in patients with heart failure enrolled in Val-HeFT.

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Device Therapy in Heart Failure by Mauricio Velez MD, Nancy K. Sweitzer MD, PhD (auth.), William H. Maisel (eds.)


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