By M.J. Elder, W. Bernauer, J.K.G. Dart, F. Bandello
Cicatrizing conjunctivitis is among the so much demanding reasons of ocular floor disorder this day, and with out acceptable intervention, corneal blindness or lack of sight from supervening an infection is usual. simply because a lot of those ailments are infrequent, there's frequently constrained administration event on hand and the assets for study into remedy and pathogenesis might be scarce. this article summarizes current therapy concepts and the medical and laboratory experiences validating those ways. issues mentioned comprise an in-depth examine non-progressive reasons together with trachoma, Stevens-Johnson syndrome and ligneous conjunctivitis. The textual content additionally examines power innovative conjunctival cicatrization, the ailments which reason it, their medical and laboratory evaluate, immunopathogenesis, sequelae and administration. it may reduction the making plans of intervention and therapy of a bunch of ailments formerly linked to terrible diagnosis.
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Among underprivileged groups living in crowded conditions as well as in tropical areas, cutaneous diptheria may remain a source of ocular infection . When suspected on clinical grounds, treatment must be prompt since the severity of systemic involvement (cardiac, peripheral nervous) depends on the amount of exotoxin absorbed prior to the eradication of the organism. After excluding hypersensitivity, diphtheria antitoxin (10,000–30,000 units increased to 40,000–100,000 units in severe cases) is administered systemically De Cock 34 Table 2.
Fibrin is a consistent feature of the ligneous membranes [28, 34, 43] (fig. 3, 4). Ligneous conjunctivitis must be distinguished from granulomatous conjunctivitis (as seen in cat scratch disease, tularaemia or tuberculosis) and conjunctival synthetic fibre granuloma . The clinical picture and the histochemical composition of the membranes suggest that the condition represents an abnormally brisk response to conjunc- Membranous, Pseudomembranous and Ligneous Conjunctivitis 39 2 Fig. 4. Histology of ligneous conjunctivitis.
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Cicatrising Conjunctivitis (Developments in Ophthalmology) by M.J. Elder, W. Bernauer, J.K.G. Dart, F. Bandello