By M. Gabriel, Ed. Khan
This booklet addresses the pharmacology and healing program of substances used to regard center ailments and high blood pressure. Additions and updates to the 6th variation contain six new chapters on present controversies in cardiac drug treatment resembling the beta blocker factor many cardiologists are almost immediately grappling with. The booklet presents functional suggestion on how one can deal with cardiac ailments and addresses the alternative of 1 specific cardiac agent vs. one other.
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This publication addresses the pharmacology and healing program of gear used to regard center ailments and high blood pressure. Additions and updates to the 6th version comprise six new chapters on present controversies in cardiac drug treatment resembling the beta blocker factor many cardiologists are almost immediately grappling with.
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Extra resources for Cardiac Drug Therapy 7th ed (Contemporary Cardiology)
5 mg daily; titrate over weeks to 25–50 mg daily, max. 5 mg twice daily; titrate over days to weeks to 25 mg twice daily 26 Cardiac Drug Therapy For the beneficial results observed in the CAPRICORN and COPERNICUS trials, see Chapter 22. Carvedilol is one of the most effective beta-blockers available and is rated by the author as the best choice for use in acute MI and post-MI prophylaxis particularly if LV dysfunction is present. ). Dosage (Further Advice) The dosage must be individualized during up-titration.
Phillips T, Anlauf M, Distler A, et al. Randomised, double blind, multicentre comparison of hydrochlorothiazide, atenolol, nitrendipine, and enalapril in antihypertensive treatment: Results of the HANE study. BMJ 1997;315:154. 51. Devreux RB. Do antihypertensive drugs differ in their abilities to regress left ventricular hypertrophy? Circulation 1997;95:1983. 52. International Collaborative Study Group. Reduction of infarct size with early use of timolol in acute myocardial infarction. N Engl J Med 1984;310:9.
Bronchial asthma is a contraindication. Chronic bronchitis and emphysema are relative contraindications depending on their severity and the necessity for beta-blockade. Severe allergic rhinitis is a relative contraindication. Avoid abrupt cessation of therapy. A worsening of angina or precipitation of acute MI has occurred on abrupt withdrawal of therapy. Although this happens only rarely, the patient must be warned. The incidence of this syndrome is said to be infrequent with pindolol because of ISA.
Cardiac Drug Therapy 7th ed (Contemporary Cardiology) by M. Gabriel, Ed. Khan