Charles L. Edelstein's Biomarkers in Kidney Disease PDF

By Charles L. Edelstein

ISBN-10: 0123756723

ISBN-13: 9780123756725

A biomarker is a molecule that's measured as a marker of standard organic strategies, affliction strategies or the reaction to a diagnostic or healing intervention. Kidney ailments like acute kidney damage, continual kidney illness, diabetic nephropathy, glomerular sickness, renal melanoma and preeclampsia nonetheless have a excessive morbidity. size of biomarkers within the blood or urine that discover sufferers prone to kidney illnesses or that become aware of kidney ailments within the earliest degree may possibly eventually bring about preventative or prior or more advantageous remedies for kidney diseases.

Biomarkers of Kidney disorder  reviews the elemental and medical examine on biomarkers of the typical kidney ailments together with acute kidney harm, persistent kidney illness, renal melanoma, diabetic nephropathy, glomerular illness and preeclampsia. The features of an incredible biomarker of kidney ailments and statistical research of biomarker stories is distinct. the most recent innovations for biomarker detection like metabolomics and proteomics is roofed within the booklet. This finished booklet info the most recent advances made within the box of biomarker examine and improvement in kidney illnesses. The e-book is a perfect better half for these attracted to biomarker study and improvement, proteomics and metabolomics, kidney ailments, statistical research, transplantation and preeclampsia.

* provides a entire, translational resource for all facets of renal biomarkers in a single reference paintings * specialists in renal affliction biomarkers (from all parts of educational and clinical learn) take readers from the bench learn (cellular and molecular mechanism) to new healing approaches

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Extra resources for Biomarkers in Kidney Disease

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J Am Soc Nephrol 2004;15:3073e82. 49. Mori K, Lee HT, Rapoport D, et al. Endocytic delivery of lipocalin siderophore iron complex rescues the kidney from ischemia reperfusion injury. J Clin Invest 2005; 115:610e21. 50. Hall IE, Yarlagadda SG, Coca SG, et al. IL 18 and urinary NGAL predict dialysis and graft recovery after kidney transplantation. J Am Soc Nephrol 2009;24:3096e102. 51. Parikh CR, Abraham E, Ancukiewicz M, et al. Urine IL 18 is an early diagnostic marker for acute kidney injury and predicts mortality in the intensive care unit.

Haase M, Fielitz Haase A, Bellomo R, et al. Sodium bicarbonate to prevent acute kidney injury after cardiac surgery: a pilot double blind, randomized controlled trial. Crit Care Med 2009;37:39e47. 94. Wagener G, Gubitosa G, Wang S, et al. Increased incidence of acute kidney injury with aprotinin use during cardiac surgery detected with urinary NGAL. Am J Nephrol 2008;28:576e82. 95. Dent CL, Ma Q, Dastrala S, et al. Plasma NGAL predicts acute kidney injury, morbidity and mortality after pediatric cardiac surgery: a prospective uncontrolled cohort study.

37. Waikar SS, Curhan GC, Wald R, et al. Declining mortality in patients with acute renal failure, 1988 to 2002. J Am Soc Nephrol 2006;17:1143e50. 38. Xue JL, Daniels F, Star RA, et al. Incidence and mortality of acute renal failure in Medicare beneficiaries, 1992 to 2001. J Am Soc Nephrol 2006;17:1135e42. 39. Ympa YP, Sakr Y, Reinhart K, et al. Has mortality from acute renal failure decreased? A systematic review of the literature. Am J Med 2005;118:827e32. 22 Michael R. Bennett and Prasad Devarajan 40.

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Biomarkers in Kidney Disease by Charles L. Edelstein

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