By American Academy of Ophthalmology, Robert H. Rosa Jr. MD
Part four provides fabrics in components: half I, Ophthalmic Pathology; and half II, Intraocular Tumors: scientific elements. half I makes use of a hierarchy that strikes from basic to precise to assist derive a differential prognosis for a selected tissue. half II is a compilation of chosen medical elements of value to the overall ophthalmologist. Following half II are the yankee Joint Committee on melanoma 2010 staging types for ocular and adnexal tumors.
Upon of completion of part four, readers can be capable to:
Describe a based method of knowing significant ocular stipulations in response to a hierarchical framework of topography, affliction technique, common prognosis and differential diagnosis
Summarize the stairs in dealing with ocular specimens for pathologic examine, together with acquiring, dissecting, processing, and marking tissues
Identify these ophthalmic lesions that point out systemic sickness and are very likely existence threatening
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Additional info for 2014-2015 Basic and Clinical Science Course (BCSC): Section 4: Ophthalmic Pathology and Intraocular Tumors
22 • Ophthalmic Pathology and lntraocular Tumors , A . B Figure 2-10 Focal posttraumatic choroidal granulomatous inflammation. A, Enucleated eye with a projectile causing a perforating limbal injury that extends to the posterior choroid . B, Microscopic examination shows a focus of choroidal granulomatous inflammation (between arrowheads). ) Rupture of the Bruch membrane or choroidal rupture may occur after direct or indirect injury to the globe. Choroidal neovascularization, granulation tissue proliferation, and scar formation may occur in an area of choroidal rupture.
D formalin diffuses at a rate of approximately 1 mm/hr; therefore, globes . drunetei, an . u, ' b fixed at ]east 12 hoLu·s prior to processing. It is generally desirable to suspend an sho~ddt". ately 10:1 for at least 24 hours prior to processing e 111 1onna eY· . dequate fixation. Differen institutions may use different protocols, and preop- to en ur ea ' . . e consultation 1s cntical. era t ,v ns >n. ild '0 ,rs as or Tissue Processing The infiltration and embedding process removes most of the water from the tissue and relaces the water with paraffin.
Courtesv of Hans E. ) Angle recession shows a rupture in the ciliary body in the plane between the external longitudinal muscle fibers and the internal circular and oblique fibers (arrow); the iris root is displaced posteriorly (arrowhead). Note the scleral spur (asterisk). Figure 2-6 dal hemorrhage. The borders of the dome-shaped choroidal hemorrhage are defined by the position of the vortex veins and the scleral spur (Fig 2-7). An iridodialysis is a rupture of the iris at the thinnest portion of the diaphragm, the iris base, where it inserts into the supportive tissue of the ciliary body (Fig 2-8).
2014-2015 Basic and Clinical Science Course (BCSC): Section 4: Ophthalmic Pathology and Intraocular Tumors by American Academy of Ophthalmology, Robert H. Rosa Jr. MD